对tPA 与AD 的相关性研究成为热点，但作用机制尚不完全明确，现对tPA 与AD 的相关研究进行综述，
Research progress of tissue-type plasminogen activator and Alzheimer disease
Tissue-type plasminogen activator（ tPA） plays an important role in intravenous thrombolysis，
and it also regulates many other non-fibrinolytic functions in the central nervous system（ CNS）. Studies have
shown that tPA have great effects on the pathological process of Alzheimer disease（ AD）. In recent years，
the correlation between tPA and AD has become a hot spot. However， at present， the mechanism about tPA
associated with AD is not fully clear. This article reviews related researches on connection between tPA and AD，
so as to improve the awareness of it.